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Aug 12, 2026 · timolol maleate (Timoptic-XE, Timoptic) (Ophthalmic Beta-Blocker) - prescribing information, mechanism of action, dosing, drug interactions, and pregnancy safety Indicated for elevated intraocular pressure in patients with ocular hypertension FDA pregnancy category C Clinical reference for healthcare professionals Find clinical guidance on Timoptic-XE, including indications, dosing, safety, side effects and evidence-based insights for healthcare professionals May 15, 2026 · Timoptic XE - Clinical Pharmacology Timoptic XE Mechanism of Action Timolol maleate is a beta 1 and beta 2 (non-selective) adrenergic receptor blocking agent that does not have significant intrinsic sympathomimetic, direct myocardial depressant, or local anesthetic (membrane-stabilizing) activity Feb 1, 2024 · Timolol gel is a beta blocker that's used to lower pressure within the eye and treat glaucoma It's a gel-forming eye drop that can be used by itself or together with other eye drops that aren't beta blockers The brand name, Timoptic-XE, was discontinued, but the generic version is still available The usual dosage is a drop of timolol gel in the eye (s) once a day A common side effect is Sep 26, 2022 · Timoptic-XE (Timolol Maleate Ophthalmic Gel Forming Solution) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources The precise mechanism of the ocular hypotensive action of TIMOPTIC-XE is not clearly established at this time Tonography and fluorophotometry studies of TIMOPTIC* (timolol maleate ophthalmic solution) in man suggest that its predominant action may be related to reduced aqueous formation Jan 28, 2014 · How Timoptic-Xe Affects Patients Timolol, when taken as eye drops, quickly reduces pressure in the eyes When taken as a tablet, it lowers blood pressure, heart rate, and amount of blood pumped by the heart It also decreases how active the sympathetic nervous system is The effects usually begin within 20 minutes of application of an eye drop dose, and can last up to 24 hours when taken in a