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Mar 16, 2026 · Non-prescription drugs, commonly called over-the-counter (OTC) drugs, are medications you can buy without a doctor’s prescription They’re available on store shelves at pharmacies, grocery stores, and gas stations, and they cover everything from headaches and allergies to heartburn and acne In the United States, the FDA regulates these products through what it calls OTC drug monographs Non-prescription drugs and medicines are Over-the-Counter (OTC) and are eligible for reimbursement with a consumer-directed healthcare plan Non-prescription drugs and medicines may be brand-name or generic How does the FDA review over-the-counter (OTC) drugs? The review of OTC medications is primarily handled by the U S Food and Drug Administration's (FDA) Division of Drug Information (CDER), the Office of Drug Evaluation, and the Nonprescription Drug Advisory Committee These teams evaluate and review OTC ingredients and labels This new module is based on the newly revised and updated 21st edition of the Handbook of Nonprescription Drugs The content is organized around topics and provides the most recent and relevant information on self-care and nonprescription medications See a cross-reference of topics by chapter in the print book Drugs com is the most popular, comprehensive and up-to-date source of drug information online Providing free, peer-reviewed, accurate and independent data on more than 24,000 prescription drugs, over-the-counter medicines & natural products Over-the-counter (OTC) medications are those that can be sold directly to people without a doctor’s prescription OTC medicines treat various diseases and their symptoms Mar 22, 2026 · A non-prescription drug is any medication you can buy without a doctor’s prescription Also called over-the-counter (OTC) drugs, these products have been determined safe and effective enough for people to use on their own, without direct supervision from a healthcare professional