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Dec 10, 2024 · VIMOVO contains naproxen as one of its active ingredients It should not be used with other naproxen-containing products since they all circulate in the plasma as the naproxen anion VIMOVO consists of an immediate-release esomeprazole magnesium layer and an enteric-coated naproxen core As a result, esomeprazole is released first in the stomach, prior to the dissolution of naproxen in the small intestine VIMOVO (esomeprazole and naproxen) is a fixed-dose combination Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX-1 and COX-2), decreasing prostaglandin synthesis, thereby reducing inflammation, pain, and fever Active ingredients The drug VIMOVO contains a combination of these active pharmaceutical ingredients (APIs):Method of administration VIMOVO tablets must be swallowed whole with water, and not split, chewed or crushed It is recommended that VIMOVO tablets are taken at least 30 minutes prior to food intake (see section 5 2) VIMOVO is a prescription medicine used in adults and adolescents, 12 years of age and older who weigh at least 84 pounds (38 kg), who need to take naproxen for relief of symptoms of arthritis and who also need to decrease the risk of developing stomach ulcers caused by naproxen Vimovo (naproxen and esomeprazole) is used to treat symptoms of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis Includes Vimovo side effects, interactions and indications